El tiempo en pantalla en el desarrollo de las actividades académicas y la salud de los estudiantes de educación superior en la modalidad en línea

: Ensuring a healthy life and promoting well-being for all is one of the main objectives of the university, but the time that adults spend in front of the screens of digital devices in the development of academic activities in the online modality is a matter of concern about possible risks to physical, mental and social health. The research findings indicate that the time that higher education students spend in front of digital device screens is causing visual health problems, eye fatigue, physical inactivity, overweight or obesity, muscle pain and spinal pain. [...]it was found that there is an association between screen time in academic activities and increased risk of the health problems mentioned above. [...]worrying levels were also found in the health of the auditory system of higher education students. Así también, la encuesta European Agency for Safety and Health at Work (2022) realizada a los empleados de establecimientos educativos europeos, estipula que el primer factor de riesgo son los trastornos musculoesqueléticos como estar sentado durante mucho tiempo frente al escritorio.

Symptoms Potentially Related to Small Fiber Neuropathy (SFN) and Anticovid Vaccines: An International Journal of Medical Toxicology and Drug Experience

Introduction: SFN is a relatively rare condition related to finer fibers of peripheral nervous system. A specific diagnostic procedure is necessary to reach a correct diagnosis.The most frequently reported symptoms are: pain (described as burning or a sensation of intense heat, as "aching cold", "pinpricks", "electric shocks),paraesthesia (spontaneous sensations of tingling,numbness,itching),dysesthesia and allodynia. Some published papers hypothesized a correlation between SFN and anticovid vaccine. Objective: Study target was to analyze the adverse events following immunization (AEFI) reported in our ASL (resident population 1,221,857, ¼ regional population) potentially linked to the SFN symptoms. Methods: Data relating to AEFI were extrapolated from the National Pharmacovigilance Network (NPN), while data referring to administered doses were extracted from the ASL QlinkView platform. Results: From 27 December 2020 to 26 April 2022, 624 reports, relating to vaccines anticovid AEFI, were received and recorded in the NPN. 2.109 AEFI were described in these reports. Administered vaccines: Comirnaty (346/624 sheets;1.164/2.109AEFI;2.092.042/ 3.028.781 total administered doses), the most reported AEFI were related to general pathologies: pain, wheal or erythema at the injection site, headache, fever, asthenia, nausea, malaise, tachycardia, muscle pain, fatigue, joint pain (25% of 1.164 AEFI). Other described symptoms: other pains, burning, itching, paraesthesia, tingling, numbness, allodynia, potentially linked to SFN (17.3% of 1.164 AEFI);Spikevax (112/624 sheets;392/2.109 AEFI;607.626/ 3.028.781 doses),the most reported AEFI, like Comirnaty, were related to the injection site (26% of 392 AEFI), while the potentially symptoms related to SFN were the 20.2% of 392 AEFI;Vaxzevria (146/624 sheets;512/2.109 AEFI;298.188/3.028.781 doses), the most reported AEFI, related to general pathologies, were the 33% of 512 AEFI, while potentially symptoms related to SFN were the 18.8%. Finally, as regards the Janssen vaccine (10/624 sheets;32/2.109 AEFI;30.702/3.028.781 doses), the most described events, related to general pathologies, are the 47% of the 32 AEFI, while 31% are potentially linked to the of SFN symptoms. No AEFI was reported related to the 223 doses about Novavax vaccine. The causality assessment was defined correlatable about 37 records (6% of 624 records). 12/37 records describe potentially linked to SFN symptoms (6 Vaxzevria (1%), 3 Comirnaty (0.5%) and 3 Spikevax (0.5%)). Conclusion: The analysis about AEFI reported in our ASL related to anticovid vaccines underlined the existence of symptoms potentially linked to SFN, although only in a few cases it was evaluated a causality assessment to vaccination. Just a specific diagnostic procedure can confirm the diagnosis and the correlation. Therefore, the correlation between SFN and vaccine needs larger-scale studies and insights for a correct evaluation.

Incidental finding of 68Ga-PSMA uptake in covid-19 induced pneumonia

A 68 years old man with prostate carcinoma was referred for 68Ga-PSMA PET/CT scan because of recent significant rise of PSA. He complained of muscle weakness and fatigue, since 3 weeks before the scan, without dyspnea or shortness of breath. In his 68Ga-PSMA-617 PET/CT study, widespread skeletal metastasis, as well as liver involvement were noticed. Also, multiple bilateral patchy areas of ground glass opacities were noticed in peripheral areas of both lung fields, which showed typical pattern of covid-19 pneumonia. These lung lesions showed relatively significant PSMA uptake which were about twice of the liver uptake. Serology test which was performed later, confirmed covid-19 infection.

Prediction of Covid-19 and post Covid-19 patients with reduced feature extraction using Machine Learning Techniques

Corona virus has spread the Covid-19 pandemic to the whole world resulting in the loss of about 3.8 million people. Nearly 156.5 million people have recovered from this disease by timely diagnostic using primary symptoms, which include lethargy caused by muscular weakness. Post Covid-19 patients also face myalgia, which is caused by the abnormal neural action potential. Electromyography (EMG) has been used for years to detect the neural communication and the action potential caused by it. Biomedical experts prefer EMG over other methods due to its ability to capture and conserve the data which helps in detecting major muscular disorders. This paper depicts multiple approaches to diagnose current Covid-19 patients or post Covid-19 patients using the EMG data of lower limb using Machine Learning. These approaches vary from each other in the form of the information conserved in the training data. The proposed method achieves the highest accuracy of 93.8% along with increasing the computational efficiency, as compared to the conventional methods. The dataset used is a publically available dataset, provided by University of California, by the name of Irvine (UCI) EMG lower limb dataset.

Outcomes of importance to children and young adults with cerebral palsy, their parents and health professionals following lower limb orthopaedic surgery: A qualitative study to inform a Core Outcome Set

IntroductionAlthough several outcomes are commonly measured to assess the effect of surgery for young people with cerebral palsy (CP), these are selected mainly by health professionals and researchers. Including the perspectives of a broader range of stakeholders is an essential step towards determining important outcomes for assessment. This qualitative study involves the development of a core outcome set (COS) for lower limb orthopaedic surgery for ambulant children with CP.ObjectiveThis study aimed to identify outcomes that matter to children and young people with CP, their parents and healthcare professionals following lower limb orthopaedic surgery.MethodsSemi‐structured interviews were conducted with 10 healthcare professionals, 10 children and young people with CP and 8 parents. Interview data were analysed by content analysis supported by the International Classification of Functioning, Disability and Health (ICF‐CY) supplemented by thematic analysis.FindingsThirty‐one outcomes were identified in total, which were linked to eleven second‐level ICF‐CY categories. There were differences between stakeholder groups in preferences and expectations from surgical outcomes. Healthcare professionals and children with their parents identified 31 and 25 outcomes, respectively. Health outcomes valued by participants were lower limb alignment and symmetry, flexibility and muscle strength, mental health, fatigue, pain, function in life, mobility, participation, being independent, quality of life and adverse events. Compared to previous published trials, 10 new outcomes were revealed by this study.ConclusionThe researchers identified outcomes that are important to all stakeholders following lower limb orthopaedic surgery for ambulant CP. Including these outcomes in future studies would promote patient‐centred care for children and young adults with CP. Findings will be used to inform an international Delphi survey and develop a COS in this field.Patient and Public ContributionThis study was informed by an advisory group including a young adult with CP and a parent of a child with CP. This group engaged in the design of the study and the information material to support the interview (information sheet and interview topic guide).